1-DNJ (Mulberry Leaf Extract (1-DNJ)) is a botanical extract derived from Morus alba leaves, standardized to 1-Deoxynojirimycin (1-DNJ). With CAS registry number 19130-96-2, this ingredient belongs to the Carb & Fat Absorption Blockers category of weight management actives. 1-DNJ is a sugar analog that competitively inhibits α-glucosidase (enzyme breaking down disaccharides into absorbable glucose). By slowing glucose absorption → reduces postprandial blood sugar spikes → less insulin → less fat storage. Parallels pharmaceutical α-glucosidase inhibitors (acarbose, miglitol) with natural origin and fewer side effects. As a B2B manufacturer, Shaanxi Baisifu Biological Engineering Co., Ltd. supplies Mulberry Leaf Extract (1-DNJ) in bulk quantities with full Certificate of Analysis (COA), ensuring consistent 1-Deoxynojirimycin (1-DNJ) content and regulatory compliance for dietary supplement, functional food, and nutraceutical applications.
Standard specifications for Mulberry Leaf Extract (1-DNJ) bulk supply from Baisifu:
1-DNJ is a sugar analog that competitively inhibits α-glucosidase (enzyme breaking down disaccharides into absorbable glucose). By slowing glucose absorption → reduces postprandial blood sugar spikes → less insulin → less fat storage. Parallels pharmaceutical α-glucosidase inhibitors (acarbose, miglitol) with natural origin and fewer side effects.
Level II. Japanese research confirms 20-30% postprandial glucose reduction (Kimura et al., 2007). Strongest evidence base in East Asian markets where mulberry leaf is traditional functional food.
Well-established safety in Japan/China (consumed as food for centuries). Mild GI effects possible (similar to acarbose but less severe). May interact with antidiabetic medications — monitor blood glucose.
Shaanxi Baisifu Biological Engineering Co., Ltd. manufactures and supplies Mulberry Leaf Extract (1-DNJ) (CAS 19130-96-2) in bulk quantities for: • Dietary supplement manufacturers (capsules, softgels, tablets, powders)
• Functional food & beverage producers
• Nutraceutical brands seeking 1-Deoxynojirimycin (1-DNJ) standardized ingredient
• Cosmetics companies (anti-cellulite, metabolic support topical) Each batch includes full Certificate of Analysis (COA) with:
• 1-Deoxynojirimycin (1-DNJ) content verification (HPLC/UV)
• Heavy metals, microbial, moisture compliance
• Pesticide residue testing (where applicable)
• Stability data and shelf life confirmation Available forms: powder extract, oil-based softgel fill, microencapsulated powder
Minimum order: 1 kg (sample quantities available)
Lead time: 7–15 business days
Packaging: 25 kg/drum, double-layer PE bag + fiber drum, nitrogen flush available
Q1: What is 1-DNJ?
Natural α-glucosidase inhibitor unique to mulberry leaves. Primary compound for blood glucose-modulating effect. 1-DNJ content varies by variety/season — standardized extracts guarantee consistent levels.
Q2: How does 1-DNJ compare to acarbose?
Same α-glucosidase inhibition mechanism but natural origin with significantly fewer GI side effects. Acarbose causes severe flatulence in 20-30%; 1-DNJ <5% at natural doses. More suitable for consumer supplements.
Q3: What 1-DNJ percentage to choose?
1-3% for standard supplements (300-500 mg/dose). 5-10% for premium formulations. Depends on target dosage and capsule size.
For complementary weight management formulations, consider combining Mulberry Leaf Extract (1-DNJ) with: Green Coffee Bean Extract, White Kidney Bean Extract, Gymnema Sylvestre Extract, Garcinia Cambogia Extract. Multi-ingredient stacks targeting different mechanisms (lipase inhibition, AMPK activation, thermogenesis, appetite suppression) produce synergistic effects superior to single-ingredient products.
About Baisifu: Shaanxi Baisifu Biological Engineering Co., Ltd. (No.69, Jinye Road, Xi'an, 710065, Shaanxi, China | Tel: 0086-29-81110978) is a GMP/ISO-certified manufacturer of botanical extracts, food flavors, amino acids, peptides, and biopesticides with 1,000+ products exported to US/EU B2B markets.
Disclaimer: This content is for informational and B2B product development purposes only. Mulberry Leaf Extract (1-DNJ) (CAS 19130-96-2) is a raw ingredient for dietary supplement and functional food formulation, not a finished consumer product. Claims cited are from published research and regulatory approvals — they do not constitute medical advice or guarantee specific outcomes. Consult regulatory experts for target market compliance.
| Parameter | Specification |
|---|---|
| 1-DNJ | 1-10% |
| Total Flavonoids | ≥5% |
| Appearance | Light yellow to brown powder |
| Solubility | Water-soluble |
| Particle Size | 80 mesh |
| Moisture | ≤5% |
| Heavy Metals | ≤10 ppm |
| GABA | Present |
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