Curcumin / Turmeric Extract

Curcumin / Turmeric Extract — CAS 458-37-7 | Bulk Supplier & Manufacturer

What is Curcumin / Turmeric Extract?

/ Curcumin / Turmeric Extract is a botanical extract derived from Curcuma longa rhizome, standardized to Curcumin. With CAS registry number 458-37-7, this ingredient belongs to the Metabolism & Lipid Regulators category of weight management actives. Curcumin activates AMPK + suppresses NF-κB (metabolism + inflammation dual regulation). AMPK → fat oxidation. NF-κB suppression → reduces chronic adipose inflammation (root cause of insulin/leptin resistance). Also inhibits angiogenesis in expanding adipose tissue (limits vascular supply for fat growth). Multi-target metabolic regulator. As a B2B manufacturer, Shaanxi Baisifu Biological Engineering Co., Ltd. supplies Curcumin / Turmeric Extract in bulk quantities with full Certificate of Analysis (COA), ensuring consistent Curcumin content and regulatory compliance for dietary supplement, functional food, and nutraceutical applications.

Curcumin / Turmeric Extract Specifications

Standard specifications for Curcumin / Turmeric Extract bulk supply from Baisifu:

How Curcumin / Turmeric Extract Works for Weight Loss

Curcumin activates AMPK + suppresses NF-κB (metabolism + inflammation dual regulation). AMPK → fat oxidation. NF-κB suppression → reduces chronic adipose inflammation (root cause of insulin/leptin resistance). Also inhibits angiogenesis in expanding adipose tissue (limits vascular supply for fat growth). Multi-target metabolic regulator.

Curcumin / Turmeric Extract Clinical Evidence & Research

Level II for weight loss. Meta-analysis: ~1 kg over 8-12 weeks. Enhanced with piperine (BioPerine®) shows 2× efficacy. Broader metabolic benefits (anti-inflammatory, insulin-sensitizing) make it valuable beyond weight loss.

Curcumin / Turmeric Extract Applications & Usage

• Metabolic health supplements (AMPK+anti-inflammatory)
• Weight management (enhanced with piperine)
• Joint+weight dual-purpose
• Liver protection
• Anti-inflammatory targeting metabolic syndrome

Curcumin / Turmeric Extract Safety & Regulatory Status

FDA GRAS. Safe at ≤1,200 mg/day. Very high doses >8 g/day may cause GI discomfort. Low oral bioavailability <5% — piperine or lipid delivery essential. No drug interactions at standard doses.

Curcumin / Turmeric Extract — B2B Bulk Supply from Baisifu

Shaanxi Baisifu Biological Engineering Co., Ltd. manufactures and supplies Curcumin / Turmeric Extract (CAS 458-37-7) in bulk quantities for: • Dietary supplement manufacturers (capsules, softgels, tablets, powders)
• Functional food & beverage producers
• Nutraceutical brands seeking Curcumin standardized ingredient
• Cosmetics companies (anti-cellulite, metabolic support topical) Each batch includes full Certificate of Analysis (COA) with:
• Curcumin content verification (HPLC/UV)
• Heavy metals, microbial, moisture compliance
• Pesticide residue testing (where applicable)
• Stability data and shelf life confirmation Available forms: powder extract, oil-based softgel fill, microencapsulated powder
Minimum order: 1 kg (sample quantities available)
Lead time: 7–15 business days
Packaging: 25 kg/drum, double-layer PE bag + fiber drum, nitrogen flush available

Curcumin / Turmeric Extract — Frequently Asked Questions

Q1: Why does Curcumin need Piperine?

<5% oral bioavailability. Piperine inhibits hepatic glucuronidation, increasing bioavailability 2,000%. Without enhancement, most curcumin wasted. Always include piperine or use phytosome/nanoemulsion delivery.

Q2: Recommended dosage?

500-1,000 mg curcuminoids/day with 5-10 mg piperine per dose. Enhanced delivery: 250-500 mg/day. ≥8 weeks needed for metabolic effects.

Related Weight-Loss Extracts

For complementary weight management formulations, consider combining Curcumin / Turmeric Extract with: Berberine, Resveratrol, Quercetin, Piperine. Multi-ingredient stacks targeting different mechanisms (lipase inhibition, AMPK activation, thermogenesis, appetite suppression) produce synergistic effects superior to single-ingredient products.

About Baisifu: Shaanxi Baisifu Biological Engineering Co., Ltd. (No.69, Jinye Road, Xi'an, 710065, Shaanxi, China | Tel: 0086-29-81110978) is a GMP/ISO-certified manufacturer of botanical extracts, food flavors, amino acids, peptides, and biopesticides with 1,000+ products exported to US/EU B2B markets.

Disclaimer: This content is for informational and B2B product development purposes only. Curcumin / Turmeric Extract (CAS 458-37-7) is a raw ingredient for dietary supplement and functional food formulation, not a finished consumer product. Claims cited are from published research and regulatory approvals — they do not constitute medical advice or guarantee specific outcomes. Consult regulatory experts for target market compliance.