(Coleus Forskohlii Extract (Forskolin)) is a botanical extract derived from Coleus forskohlii root, standardized to Forskolin. With CAS registry number 66575-29-9, this ingredient belongs to the Fat Oxidation & Thermogenesis category of weight management actives. Forskolin directly activates adenylate cyclase → converts ATP to cAMP → activates PKA → phosphorylates hormone-sensitive lipase → triglyceride breakdown (lipolysis). Also increases thermogenic activity in BAT and enhances thyroid hormone production (increasing BMR). Direct cAMP elevation makes forskolin mechanistically distinct from other botanical ingredients. As a B2B manufacturer, Shaanxi Baisifu Biological Engineering Co., Ltd. supplies Coleus Forskohlii Extract (Forskolin) in bulk quantities with full Certificate of Analysis (COA), ensuring consistent Forskolin content and regulatory compliance for dietary supplement, functional food, and nutraceutical applications.
Standard specifications for Coleus Forskohlii Extract (Forskolin) bulk supply from Baisifu:
Forskolin directly activates adenylate cyclase → converts ATP to cAMP → activates PKA → phosphorylates hormone-sensitive lipase → triglyceride breakdown (lipolysis). Also increases thermogenic activity in BAT and enhances thyroid hormone production (increasing BMR). Direct cAMP elevation makes forskolin mechanistically distinct from other botanical ingredients.
Level II. Godard et al. (2005) showed forskolin 250 mg/day produced 8.8% body fat reduction and 7.8% lean mass increase in overweight men over 12 weeks, without diet modification. Less consistent results in women.
May lower blood pressure (cAMP-mediated vasodilation). Caution with antihypertensive medications. Avoid with beta-blockers (oppose cAMP signaling). May increase heart rate at high doses. Not for bleeding disorders. Pregnancy: insufficient data.
Shaanxi Baisifu Biological Engineering Co., Ltd. manufactures and supplies Coleus Forskohlii Extract (Forskolin) (CAS 66575-29-9) in bulk quantities for: • Dietary supplement manufacturers (capsules, softgels, tablets, powders)
• Functional food & beverage producers
• Nutraceutical brands seeking Forskolin standardized ingredient
• Cosmetics companies (anti-cellulite, metabolic support topical) Each batch includes full Certificate of Analysis (COA) with:
• Forskolin content verification (HPLC/UV)
• Heavy metals, microbial, moisture compliance
• Pesticide residue testing (where applicable)
• Stability data and shelf life confirmation Available forms: powder extract, oil-based softgel fill, microencapsulated powder
Minimum order: 1 kg (sample quantities available)
Lead time: 7–15 business days
Packaging: 25 kg/drum, double-layer PE bag + fiber drum, nitrogen flush available
Q1: What forskolin percentage should I choose?
10% forskolin extract at 250 mg/capsule (delivering 25 mg pure forskolin) is most clinically validated. 20% allows smaller capsules at same delivery. 40% and 98% for specialized formulations.
Q2: Is Forskolin safe for people with high blood pressure?
Forskolin naturally lowers BP through cAMP vasodilation — beneficial for hypertensive individuals but may cause hypotension combined with BP medications. Monitor BP when starting supplementation.
Q3: How does Forskolin compare to Green Tea Extract?
Forskolin works upstream (adenylate cyclase → cAMP → PKA → lipase), EGCG downstream (AMPK → metabolic shift). They target different nodes — complementary rather than competing.
For complementary weight management formulations, consider combining Coleus Forskohlii Extract (Forskolin) with: Green Tea Extract, Capsaicin, Yohimbine HCl, Black Ginger Extract. Multi-ingredient stacks targeting different mechanisms (lipase inhibition, AMPK activation, thermogenesis, appetite suppression) produce synergistic effects superior to single-ingredient products.
About Baisifu: Shaanxi Baisifu Biological Engineering Co., Ltd. (No.69, Jinye Road, Xi'an, 710065, Shaanxi, China | Tel: 0086-29-81110978) is a GMP/ISO-certified manufacturer of botanical extracts, food flavors, amino acids, peptides, and biopesticides with 1,000+ products exported to US/EU B2B markets.
Disclaimer: This content is for informational and B2B product development purposes only. Coleus Forskohlii Extract (Forskolin) (CAS 66575-29-9) is a raw ingredient for dietary supplement and functional food formulation, not a finished consumer product. Claims cited are from published research and regulatory approvals — they do not constitute medical advice or guarantee specific outcomes. Consult regulatory experts for target market compliance.
| Parameter | Specification |
|---|---|
| Forskolin | 10%, 20%, 40%, 98% |
| Appearance | Light yellow to brown powder |
| Solubility | Ethanol-soluble; limited water solubility |
| Particle Size | 80 mesh |
| Moisture | ≤5% |
| Heavy Metals | ≤10 ppm |
| Total Ash | ≤5% |
| Microbial | E. coli/Salmonella negative |
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