Antioxidant & Metabolic Support

Alpha-Lipoic Acid (ALA)

Alpha-Lipoic Acid (ALA) — CAS 1200-22-2 | Bulk Supplier & Manufacturer

What is Alpha-Lipoic Acid (ALA)?

ALA (Alpha-Lipoic Acid (ALA)) is a botanical extract derived from Synthetic; also biosynthesized in mitochondria, standardized to Alpha-Lipoic Acid (pure). With CAS registry number 1200-22-2, this ingredient belongs to the Antioxidant & Liver/Metabolic Support category of weight management actives. Unique water+lipid dual-soluble antioxidant. Activates AMPK, improves insulin sensitivity (GLUT4 translocation), recycles other antioxidants (Vitamin C, E, glutathione, CoQ10). R-ALA 300 mg/day reduces waist circumference 2.1 cm over 4 months (Kurgan study). Specifically targets abdominal fat. As a B2B manufacturer, Shaanxi Baisifu Biological Engineering Co., Ltd. supplies Alpha-Lipoic Acid (ALA) in bulk quantities with full Certificate of Analysis (COA), ensuring consistent Alpha-Lipoic Acid (pure) content and regulatory compliance for dietary supplement, functional food, and nutraceutical applications.

Alpha-Lipoic Acid (ALA) Specifications

Standard specifications for Alpha-Lipoic Acid (ALA) bulk supply from Baisifu:

How Alpha-Lipoic Acid (ALA) Works for Weight Loss

Unique water+lipid dual-soluble antioxidant. Activates AMPK, improves insulin sensitivity (GLUT4 translocation), recycles other antioxidants (Vitamin C, E, glutathione, CoQ10). R-ALA 300 mg/day reduces waist circumference 2.1 cm over 4 months (Kurgan study). Specifically targets abdominal fat.

Alpha-Lipoic Acid (ALA) Clinical Evidence & Research

Level II. Kurgan et al. showed R-ALA 300 mg/day significantly reduced waist circumference and abdominal fat. Weight loss modest ~1 kg over 4 months but abdominal fat specificity valuable.

Alpha-Lipoic Acid (ALA) Applications & Usage

  • Insulin sensitivity supplements
  • Abdominal fat reduction formulas
  • Antioxidant+metabolic health dual
  • Diabetes-prevention nutraceuticals
  • GLUT4 enhancer positioning

Alpha-Lipoic Acid (ALA) Safety & Regulatory Status

Very safe at 300-600 mg/day. FDA approved for diabetic neuropathy treatment in Germany (600 mg/day). R-ALA ~10× more potent than S-ALA. May lower blood glucose — monitor with antidiabetic meds.

Alpha-Lipoic Acid (ALA) — B2B Bulk Supply from Baisifu

Shaanxi Baisifu Biological Engineering Co., Ltd. manufactures and supplies Alpha-Lipoic Acid (ALA) (CAS 1200-22-2) in bulk quantities for: • Dietary supplement manufacturers (capsules, softgels, tablets, powders)
• Functional food & beverage producers
• Nutraceutical brands seeking Alpha-Lipoic Acid (pure) standardized ingredient
• Cosmetics companies (anti-cellulite, metabolic support topical) Each batch includes full Certificate of Analysis (COA) with:
• Alpha-Lipoic Acid (pure) content verification (HPLC/UV)
• Heavy metals, microbial, moisture compliance
• Pesticide residue testing (where applicable)
• Stability data and shelf life confirmation Available forms: powder extract, oil-based softgel fill, microencapsulated powder
Minimum order: 1 kg (sample quantities available)
Lead time: 7–15 business days
Packaging: 25 kg/drum, double-layer PE bag + fiber drum, nitrogen flush available

Alpha-Lipoic Acid (ALA) — Frequently Asked Questions

Q1: R-ALA vs. S-ALA?

R-ALA is natural isomer with ~10× greater biological activity. S-ALA is synthetic byproduct. Premium supplements should use pure R-ALA. Standard "ALA" = 50/50 R+S mix — only half active.

Q2: Why "universal antioxidant"?

Only antioxidant soluble in both water and lipid environments. Protects every cellular compartment. Also regenerates oxidized Vitamin C, E, glutathione, CoQ10 — recycling entire antioxidant network.

Related Weight-Loss Extracts

For complementary weight management formulations, consider combining Alpha-Lipoic Acid (ALA) with: CoQ10, Berberine, Curcumin, Astaxanthin. Multi-ingredient stacks targeting different mechanisms (lipase inhibition, AMPK activation, thermogenesis, appetite suppression) produce synergistic effects superior to single-ingredient products.

About Baisifu: Shaanxi Baisifu Biological Engineering Co., Ltd. (No.69, Jinye Road, Xi'an, 710065, Shaanxi, China | Tel: 0086-29-81110978) is a GMP/ISO-certified manufacturer of botanical extracts, food flavors, amino acids, peptides, and biopesticides with 1,000+ products exported to US/EU B2B markets.

Disclaimer: This content is for informational and B2B product development purposes only. Alpha-Lipoic Acid (ALA) (CAS 1200-22-2) is a raw ingredient for dietary supplement and functional food formulation, not a finished consumer product. Claims cited are from published research and regulatory approvals — they do not constitute medical advice or guarantee specific outcomes. Consult regulatory experts for target market compliance.

Parameter Specification
ALA ≥99%
R-ALA ≥99% (R-isomer premium)
Appearance Yellow crystalline powder
Solubility Limited water/ethanol-soluble
Particle Size 80 mesh
Moisture ≤2%
Heavy Metals ≤10 ppm

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