5-HTP / Griffonia Seed Extract

5-HTP / Griffonia Seed Extract — CAS 4350-09-8 | Bulk Supplier & Manufacturer

What is 5-HTP / Griffonia Seed Extract?

5-5-HTP (5-HTP / Griffonia Seed Extract) is a botanical extract derived from Griffonia simplicifolia seeds, standardized to 5-HTP. With CAS registry number 4350-09-8, this ingredient belongs to the Appetite Suppressants & Satiety category of weight management actives. 5-HTP is direct serotonin precursor (bypasses rate-limiting tryptophan hydroxylase step). Increased hypothalamic serotonin activates POMC satiety neurons, reduces NPY hunger neuropeptides, specifically reduces carbohydrate cravings. As a B2B manufacturer, Shaanxi Baisifu Biological Engineering Co., Ltd. supplies 5-HTP / Griffonia Seed Extract in bulk quantities with full Certificate of Analysis (COA), ensuring consistent 5-HTP content and regulatory compliance for dietary supplement, functional food, and nutraceutical applications.

5-HTP / Griffonia Seed Extract Specifications

Standard specifications for 5-HTP / Griffonia Seed Extract bulk supply from Baisifu:

How 5-HTP / Griffonia Seed Extract Works for Weight Loss

5-HTP is direct serotonin precursor (bypasses rate-limiting tryptophan hydroxylase step). Increased hypothalamic serotonin activates POMC satiety neurons, reduces NPY hunger neuropeptides, specifically reduces carbohydrate cravings.

5-HTP / Griffonia Seed Extract Clinical Evidence & Research

Level II. Cangiano et al. (1992) showed 750 mg/day produced 2.3 kg weight loss over 5 weeks without dietary restrictions. Stronger effect in carb-cravers and low-serotonin individuals.

5-HTP / Griffonia Seed Extract Applications & Usage

• Appetite suppressant supplements (serotonin pathway)
• Weight management+mood support
• Carbohydrate craving control
• Emotional eating support
• Night-time appetite control

5-HTP / Griffonia Seed Extract Safety & Regulatory Status

⚠ Do NOT combine with SSRIs/MAOIs — serotonin syndrome risk (potentially fatal). Common: nausea/vomiting/diarrhea >300 mg/day. Start 50-100 mg/day. Not for pregnant/lactating women.

5-HTP / Griffonia Seed Extract — B2B Bulk Supply from Baisifu

Shaanxi Baisifu Biological Engineering Co., Ltd. manufactures and supplies 5-HTP / Griffonia Seed Extract (CAS 4350-09-8) in bulk quantities for: • Dietary supplement manufacturers (capsules, softgels, tablets, powders)
• Functional food & beverage producers
• Nutraceutical brands seeking 5-HTP standardized ingredient
• Cosmetics companies (anti-cellulite, metabolic support topical) Each batch includes full Certificate of Analysis (COA) with:
• 5-HTP content verification (HPLC/UV)
• Heavy metals, microbial, moisture compliance
• Pesticide residue testing (where applicable)
• Stability data and shelf life confirmation Available forms: powder extract, oil-based softgel fill, microencapsulated powder
Minimum order: 1 kg (sample quantities available)
Lead time: 7–15 business days
Packaging: 25 kg/drum, double-layer PE bag + fiber drum, nitrogen flush available

5-HTP / Griffonia Seed Extract — Frequently Asked Questions

Q1: What is 5-HTP for weight loss?

Direct serotonin precursor. Increased brain serotonin suppresses appetite by activating satiety neurons and reducing hunger neuropeptides. Particularly reduces carb cravings.

Q2: Can take with antidepressants?

No. SSRIs prevent serotonin reuptake; 5-HTP increases production. Combined → serotonin syndrome risk (potentially fatal). Use alone or under professional supervision.

Q3: Recommended dosage?

50-100 mg 2-3× daily, 30 min before meals. Start at 50 mg. Total ≤300 mg/day without supervision.

Related Weight-Loss Extracts

For complementary weight management formulations, consider combining 5-HTP / Griffonia Seed Extract with: Saffron Extract, Ashwagandha Extract, Fenugreek Extract, African Mango Seed Extract. Multi-ingredient stacks targeting different mechanisms (lipase inhibition, AMPK activation, thermogenesis, appetite suppression) produce synergistic effects superior to single-ingredient products.

About Baisifu: Shaanxi Baisifu Biological Engineering Co., Ltd. (No.69, Jinye Road, Xi'an, 710065, Shaanxi, China | Tel: 0086-29-81110978) is a GMP/ISO-certified manufacturer of botanical extracts, food flavors, amino acids, peptides, and biopesticides with 1,000+ products exported to US/EU B2B markets.

Disclaimer: This content is for informational and B2B product development purposes only. 5-HTP / Griffonia Seed Extract (CAS 4350-09-8) is a raw ingredient for dietary supplement and functional food formulation, not a finished consumer product. Claims cited are from published research and regulatory approvals — they do not constitute medical advice or guarantee specific outcomes. Consult regulatory experts for target market compliance.