029-81163280
13519147002
Purity: 99%
Place of Origin: Shaanxi, China
Brand Name: BAISFU
Type: Plant extract
Form: Powder
Product Name:Camptothecine
Storage: Dark seal, should be stored in a cool, dry, ventilated warehouse
Purity: 99%
Shelf Life: 2 years
Original: Shaanxi, China
MOQ: 5 kg
Selling Units: Single item
Single package size: 55.6X32.75X27.05 cm
Single gross weight: 2.000 kg
Ideal Medical Intermediates for Cancer Busters Camptothecin
Camptothecin is a plant anticancer drug with the chemical formula C20H16N2O4 and light yellow acicular crystal. It was extracted from Camptotheca acuminata distributed in central and southwest China. In 1976, Chinese chemist Gao Yisheng and others successfully synthesized racemocytothecin. Camptothecin has a good effect on gastrointestinal tract and head and neck cancer, but has the side effect of urine blood in a few patients. The anticancer activity of 10-hydroxycamptothecin is more than that of camptothecin, and it also has obvious curative effect on liver cancer and head and neck cancer with fewer side effects. Camptothecin (CPT) is a cytotoxic quinoline alkaloid that inhibits DNA topoisomerase (TOPO I). In 1966, M.E. Wall and M.C. Wani discovered anticancer drugs through systematic screening of natural substances.
Camptothecin was isolated from the bark and branches of the Camptotheca acacia tree (Camptotheca acacia) native to China and was early used in traditional Chinese medicine to treat cancer. Camptothecin in preliminary clinical trials showed significant anticancer properties, low solubility and high adverse drug reaction characteristics. Medicinal chemists have taken advantage of these properties to develop a variety of synthetic camptothecin and various derivatives to increase the good effect. Two analogs of camptothecin have been approved for cancer chemotherapy, such as topotecan and irinotecan.
Appearance and properties: light yellow crystal powder
Density: 1.51g /cm3
Melting point: 260 °C (dec.)(lit.)
Boiling point: 264ºC
Flash point: 411.6ºC
Refractive index: 1.787
Water solubility: insoluble
Storage conditions: Low temperature, ventilation and dry warehouse, separate from food raw materials
Light yellow acicular crystal. Melting point 264 ~ 267℃, [α]D20+31.3°(chloroform: methanol =1∶2). Insoluble in water, soluble in chloroform, methanol, ethanol. The solution shows purple-blue fluorescence under ultraviolet lamp, easily metamorphic in light, slightly hygroscopic, yellowish-green in case of concentrated sulfuric acid, diluted with distilled water to produce yellowish-green fluorescence, which is alkaline. It reacts with bismuth potassium iodide to form an orange-red double salt precipitate. It is obtained by extracting the root or fruit powder in organic solvent. It is highly toxic and should be extracted with care. It has anti-tumor activity. Used to treat bowel cancer, rectal cancer, gastric cancer and leukemia, 10-hydroxycamptothecin is less toxic.
Ideal Medical Intermediates for Cancer Busters Camptothecin
Camptothecin (CPT) is a cytotoxic quinoline alkaloid that inhibits DNA topoisomerase (TOPO I). In 1966, M.E. Wall and M.C. Wani discovered anticancer drugs through systematic screening of natural substances.
Camptothecin was isolated from the bark and branches of the Camptotheca acacia tree (Camptotheca acacia) native to China and was early used in traditional Chinese medicine to treat cancer. Camptothecin in preliminary clinical trials showed significant anticancer properties, low solubility and high adverse drug reaction characteristics. Medicinal chemists have taken advantage of these properties to develop a variety of synthetic camptothecin and various derivatives to increase the good effect. Two analogs of camptothecin have been approved for cancer chemotherapy, such as topotecan and irinotecan.
1. Digestive system cancer: The effect on gastric cancer is better, the obvious effect is fast, but the remission period is short (average 2 to 3 months). It also has a certain effect on esophageal cancer, cardiac cancer, colon cancer, rectal cancer and primary liver cancer. 2. Others: such as acute and chronic myelogenous leukemia, chorionic epithelial cancer, lung cancer, bladder cancer, etc.
Shaanxi Baisfu Bioengineering Co., Ltd. is an enterprise specializing in the research and development, production and sales of flavors and fragrances. The company is located in Building A, Baodeyun Valley, No. 52, Jinye 1st Road, Yanta District, Xi'an City, Shaanxi Province. It has an excellent geographical location and convenient transportation. convenient. The company was established in December 2019, with a registered capital of 3 million yuan.
The company's main products include cooling agents, synthetic flavors and natural flavors. The company's products can be used in food and beverage, daily chemical, and other industries, and have a wide range of downstream applications.
The company always attaches great importance to product quality and brand reputation, strictly implements product quality and environmental management control, and has passed various certifications such as GPM, ISO9001, ISO14001, kosher, and HALAL European analysis.
The company's products are used by more than 30 foreign companies and regions. After more than ten years of technology accumulation and market development, the company has accumulated a group of high-quality customer groups, stable customer channels and resources, and has established relationships with more than 100 domestic and foreign companies. Good working relations.
Ideal Medical Intermediates for Cancer Busters Camptothecin
Package: 1kg per bag with double plastic inside and aluminium foil bag outside, or 25kg per fibre drum with double plastic bag inside, or according to customers' requirement.
Storage: Store in cool & dry place. Keep away from strong light and heat.
Delivery: 1-2 working days after payment/FedEx, DHL, TNT, EMS, etc.
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